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High bilirubin , which often causes jaundice, can result from liver damage or gallstones. Symptoms include yellowing skin and dark urine. What does it mean to have high bilirubin ? We’ll go over the meaning, symptoms, and causes of high bilirubin levels, as well as how to treat it. The total bilirubin blood test functions as a critical diagnostic method to determine complete total serum bilirubin bloodstream concentrations, which helps medical practitioners detect liver dysfunctions and blood cell metabolic indicators and general health-related conditions. This article defines bilirubin and examines the causes of elevated bilirubin levels in adults and newborns. It also looks at the symptoms and treatment options for high bilirubin levels.