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Metabolic syndrome is a multiplex risk factor that arises from insulin resistance accompanying abnormal adipose deposition and function. It is a risk factor for coronary heart disease, as well as diabetes, fatty liver, and several cancers. Metabolic syndrome is a group of conditions that increase the risk of heart disease, stroke and type 2 diabetes . These conditions include high blood pressure, high blood sugar, too much fat around the waist, and high cholesterol or triglyceride levels. What Is Metabolic Syndrome ? Metabolic syndrome is a group of five risk factors that can lead to heart disease, diabetes, stroke and other health problems. It is diagnosed when someone has three or more of these conditions: Metabolic syndrome is a cluster of conditions that increase the risk of heart disease, stroke, and type 2 diabetes. It is becoming increasingly common worldwide, largely due to changes in lifestyle, diet, and rising rates of obesity.