What is a Double Marker Test ? The Double Marker Test , also known as the dual marker test is a blood screening that checks for 2 major substances in the mother’s blood sample. The test is generally recommended between the 9th and 12th weeks of pregnancy . Learn about the Double Marker Test in pregnancy , its uses, test results, procedures, and normal range values. Understand the dual marker test report and its significance. The Double Marker Test (also known as the dual marker test) is a prenatal screening performed during the first trimester of pregnancy . It helps assess the risk of chromosomal abnormalities in the developing baby, such as Down syndrome, Edward syndrome, and Patau syndrome. The double marker test is a simple blood test usually done during early pregnancy , typically between the 11th and 14th week. Its main purpose is to check the risk of certain chromosomal abnormalities in the developing baby, such as: