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Explore the causes of constant thirst, such as dehydration, diabetes, and anemia . Learn how to manage excessive thirst and when to seek medical advice. The meaning of THIRST is a sensation of dryness in the mouth and throat associated with a desire for liquids; also : the bodily condition (as of dehydration) that induces this sensation. Thirst , like hunger, is usually pretty cut and dry. You feel thirsty —usually because you've been sweating a lot or not getting enough fluids—drink water, and no longer feel thirsty . But what... Family medicine specialist Matthew Goldman, MD, explains that there can be multiple reasons why you’re thirsty all of a sudden — and some are more serious than others. “ Thirst is a defense mechanism,” says Dr. Goldman. In other words, this is your body’s way of letting you know that your fluid levels are imbalanced.