Rarely other organisms, such as Shigella and Streptococcus pneumoniae, are implicated. Acute kidney injury necessitating dialysis develops in approximately half of children with diarrhea-associated HUS. Adequate hydration is important to minimize renal damage in HUS associated with Shiga toxin-producing E coli infections. Diarrhoea can be defined as the passage of: Based on duration, diarrhoea is classified as: Shigella is a genus of the Enterobacteriaceae family, consisting of four species of aerobic, nonmotile, non-lactose-fermenting gram-negative rods: S sonnei, S flexneri, S boydii, and S dysenteriae. Shigellosis may spread from person to person (by fecal-oral contact), and via contaminated water and food. Raramente, estão envolvidos outros organismos, como Shigella e Streptococcus pneumoniae. A lesão renal aguda que requer diálise ocorre em aproximadamente metade das crianças com SHU associada à diarreia.