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Learn more about how semaglutide works, its side effects, and what to expect when taking this medication. RYBELSUS ( semaglutide) tablets , for oral use Initial U.S. Approval: 2017 WARNING: RISK OF THYROID C-CELL TUMORS See full prescribing information for complete boxed warning. Semaglutide is used in the case of Semaglutide is used in the treatment of Type 2 diabetes mellitus. The detailed uses of Semaglutide are as follows: • Type 2 Diabetes Management: Semaglutide is primarily prescribed to help manage blood sugar levels in individuals with type 2 diabetes. • Improving Glycemic Control: Semaglutide works by stimulating insulin secretion in response to meals, which helps in maintaining better overall glycemic control for patients with diabetes. • Reduced ... Semaglutide is a prescription medication used to treat the symptoms of Type 1 Diabetes Mellitus and Weight Management. Learn about side effects, drug interactions, dosages, warnings, and more.