Promiscuous means having a lot of different sexual partners or sexual relationships, or involving a lot of different partners. Learn more about the word, its pronunciation, synonyms, and translations in different languages. Promiscuous means having sex with many different people or including a wide range of different things. Learn more about the word origin, synonyms, antonyms, and usage examples of promiscuous . Definition of promiscuous adjective in Oxford Advanced Learner's Dictionary. Meaning , pronunciation, picture, example sentences, grammar, usage notes, synonyms and more. The meaning of PROMISCUOUS is having or involving many sexual partners : not restricted to one sexual partner or few sexual partners. How to use promiscuous in a sentence. The Multiple Meanings of Promiscuous