Mannitol is widely used in the management of raised intracranial pressure (ICP), for renal protection in cardiac, vascular, and renal trans-plantation surgery, and in the management of rhabdomyolysis. It has also previously been used for bowel preparation before colorectal surgery. In this article, we discuss the current evidence for the use of mannitol in a variety of clinical situations. Mannitol is an antihypertensive agent belonging to Osmosis Diuretics. Mannitol is an Osmotic diuretic used to remove excess water and toxins from the body in patients with kidney disease. It is also used in the treatment of cerebral edema and intraocular pressure. Approximately 7% of ingested mannitol is absorbed during gastrointestinal perfusion in uremic patients. Mannitol administered intravenously has a volume of distribution of 34.3 L. Mannitol is metabolized only slightly, if at all ... Mannitol IV 20% Injection is a medicine used in the treatment of acute renal (kidney) failure, cerebral edema (accumulation of excessive fluid in the brain) and to reduce the pressure inside the eyes in a condition called glaucoma. Mannitol is a diuretic used to force urine production in people with acute (sudden) kidney failure. Mannitol injection is also used to reduce swelling and pressure inside the eye or around the brain. Learn about side effects, drug interactions, and more.
