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To help deter misuse and abuse of OTC loperamide products, FDA has approved packaging changes for several tablet and capsule formulations of the drug (including Imodium brand-name products) that limit total loperamide hydrochloride content of the package to 48 mg and require use of single-dose (e.g., blister) packaging. Loperamide is a medicine used to treat diarrhea and reduce the amount of poop after an ileostomy. Learn about its dosage forms, common side effects, serious risks, and interactions with other medicines. Loperamide Hcl 2 MG Tablet is a very effective anti-diarrhea medication. It is used to relieve the symptoms of diarrhea that start suddenly and lasts for a few days.