Immunoglobulin A (IgA) nephropathy is deposition of IgA immune complexes in glomeruli, manifesting as slowly progressive hematuria, proteinuria, and, often, chronic kidney disease. Diagnosis is based on urinalysis and renal biopsy. Treatment options include angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), corticosteroids and sometimes other immunosuppressants. Prognosis is generally good. Immunoglobulin A (IgA) nephropathy (also known as Berger disease) was first described by Berger and Hinglais in 1968. IgA nephropathy is characterized by predominant IgA deposition in the glomerular mesangium. Iga Nephropathy: Understanding a Common Kidney Condition Introduction IgA nephropathy, also known as Berger's disease, is a kidney disorder that occurs when immunoglobulin A (IgA) deposits build up in the kidneys, leading to inflammation and damage. This condition is significant because it is one of the most common causes of kidney disease worldwide, particularly in young adults and adolescents. Understanding IgA nephropathy is crucial for early diagnosis and effective management, which can ... IgA nephropathy (nuh-FROP-uh-thee), also known as Berger disease, is a kidney disease. It happens when a germ-fighting protein called immunoglobulin A (IgA) builds up in the kidneys.
