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Learn about the anatomy of the heart and how its chambers, valves, and vessels work together to maintain effective blood circulation throughout the body to sustain life. How does the heart work? Find out with detailed explanations of its anatomy, blood circulation pathways, and the essential functions of this life-sustaining pump. Learn about the four main functions of the heart, such as pumping blood, hormones and waste products, and maintaining blood pressure. Find out the common heart diseases, such as coronary artery disease, angina, arrhythmia and heart failure, and how to diagnose them with cardiac catheterization. Heart Definition The heart is a muscular organ that pumps blood throughout the body. It is located in the middle cavity of the chest, between the lungs. In most people, the heart is located on the left side of the chest, beneath the breastbone. The heart is composed of smooth muscle. It has four chambers which contract in a specific order, allowing the human heart to pump blood from the body to the lungs and back again with high efficiency. The heart also contains “pacemaker” cells which ...