Harlequin baby: Learn about Harlequin Ichthyosis

Learn about Harlequin Ichthyosis, including symptoms, causes, and treatments. If you or a loved one is affected by this condition, visit NORD to find Harlequin ichthyosis is the most severe form of autosomal recessive congenital ichthyosis. Harlequin ichthyosis is characterized by a profound thickening of the keratin layer in fetal skin. Harlequin ichthyosis, sometimes called Harlequin baby syndrome or congenital ichthyosis, is a rare condition affecting the skin. It’s a type of ichthyosis, which refers to a group of disorders ... Harlequin ichthyosis is a severe, lifelong condition that affects a newborn's skin causing dry, scaly skin. Read on for the signs, symptom, causes, and more.