Glow definition: a light emitted by or as if by a substance heated to luminosity; incandescence.. See examples of GLOW used in a sentence. Used to describe something naturally luminescent, often associated with the night. Firefly larvae glow softly in the garden. Sometimes 'glow' signifies hope or positivity in a situation that seems dark. Her kindness was a glow in the troubled times. Dr. Varshini Reddy started Glow as a skincare destination that could serve as a clinic, medispa and a rest stop for you to indulge in some self-care. Apart from being a dermatologist, she is also a skincare enthusiast who is here to share all her clinical know-how and experience. 12 meanings: 1. light emitted by a substance or object at a high temperature 2. a steady even light without flames 3..... Click for more definitions.