Glucose-6-phosphate dehydrogenase ( G6PD) deficiency is an X-linked recessive enzymatic disorder, particularly prevalent in Africa, Asia and the Middle East. In the US, about 14% of black men are affected. Individuals with G6PD deficiency are often ... Overview G6PD deficiency is a genetic condition in which the body lacks enough of an enzyme (glucose-6-phosphate dehydrogenase) that helps protect red blood cells. It is caused by mutations in the G6PD gene and can lead to red blood cell breakdown when exposed to certain triggers, such as infections, certain foods (e.g., fava beans), or ... yme is critical to protecting erythrocytes against oxidative stress, and deficiency may lead to hemolysis in the presence of certain environmental factors such as infection and some medications and foods. Neonatal jaundice, favism, and hemolysis are associated with exposure to increased oxidative stressors in patients with G6PD deficiency . By recognizing the potential for G6PD deficiency , clinicians can screen for the disorder and teach affected patients how to avoid triggers that result in ... Glucose- 6-phosphate dehydrogenase (G6PD) deficiency is an inherited genetic disorder that can result in destruction of red blood cells (hemolysis) after an acute illness or use of certain medications.

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