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This is using the energy released by the electrons as they travel through the electron transport chain . In aerobic respiration, chemiosmosis is the process where H + ions diffuse from the intermembrane space of the mitochondrion to the matrix, through the ATP synthase in the inner mitochondrial membrane. It contains the electron transport chain (ETC) complexes. Electron Transport Chain (ETC): The ETC is depicted as a series of protein complexes embedded in the IMM. These complexes (e.g., Complexes I, II, III, and IV) facilitate the transfer of electrons from electron donors (e.g., NADH, FADH2) to electron acceptors. Electron transport chain inhibitors such as rotenone, antimycin, and cyanide block specific steps in the electron transport system, which ultimately leads to a decrease in ATP production through cellular respiration. This results in the inability of the cell to meet its energy demands, leading to cellular dysfunction and potential cell death. The electron transport chain is a series of four protein complexes, along with accessory electron carriers, e mbedded in the inner mitochondrial membrane of mitochondria.