Diethylcarbamazine: Pharmacodynamics Diethylcarbamazine is an anthelmintic

Pharmacodynamics Diethylcarbamazine is an anthelmintic drug that does not resemble other antiparasitic compounds. It is a synthetic organic compound which is highly specific for several parasites and does not contain any toxic metallic elements. Mechanism of action The mechanism of action of diethylcarbamazine is thought to involve sensitizing the microfilariae to phagocytosis. One study showed that diethylcarbamazine 's activity against Brugia malayi microfilariae is dependent on inducible ... Diethylcarbamazine is a medication used to treat filarial diseases such as lymphatic filariasis, loiasis, and tropical pulmonary eosinophilia. It is an inhibitor of arachidonic acid metabolism in microfilariae and is on the WHO List of Essential Medicines. Diethylcarbamazine is used to treat certain parasitic diseases caused by infection with roundworms of the Filarioidea type, including lymphatic filariasis caused by infection with Wuchereria bancrofti, Brugia malayi, or Brugia timori; tropical pulmonary eosinophilia; and loiasis. Diethylcarbamazine is an antihelmintic drug that treats worm infections such as filariasis, loiasis and eosinophilic lung. Learn about its indications, contraindications, side effects, precautions and drug interactions.