Combiflam Tablet is a painkiller that contains ibuprofen and paracetamol. It is used to treat inflammation and pain caused by various conditions, but it has some contraindications and interactions. Learn more about its dosage, substitutes, price and FAQs. Combiflam Tablet is composed of two medicines, namely Ibuprofen and Paracetamol. Ibuprofen is known to have an analgesic and anti-inflammatory effect for reducing mild to moderate pain. It works by blocking the effect of a chemical known as prostaglandin, responsible for inducing pain and inflammation in our body. Paracetamol acts as a mild analgesic and antipyretic (fever reducer). It lowers the elevated body temperature and mild pain by inhibiting the synthesis of a chemical messenger ... Combiflam Tablet contains two painkiller medicines. They work together to reduce pain, fever, and inflammation. It is used to treat many conditions such as headache, muscle pain, pain during periods, toothache, and joint pain. Combiflam Tablet is best taken with food to reduce side effects. Combiflam is a non-selective inhibitor of cyclooxygenase, an enzyme invovled in prostaglandin synthesis via the arachidonic acid pathway. Its pharmacological effects are believed to be due to inhibition cylooxygenase-2 (COX-2) which decreases the synthesis of prostaglandins involved in mediating inflammation, pain, fever and swelling. Antipyretic effects may be due to action on the hypothalamus, resulting in an increased peripheral blood flow, vasodilation, and subsequent heat dissipation ...
