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The classic coagulation cascade model of intrinsic and extrinsic coagulation pathways, i.e. contact activation pathway and tissue factor pathway, has been widely modified. The cascade can be categorized as follows: 1) initiation by tissue factor ... COAGULATION definition: 1. the process by which blood changes into a solid state to form a solid seal 2. the process by…. Learn more. Coagulation is the formation of a blood clot, and is essential to haemostasis. Haemostasis is the body’s physiological response to damaged blood vessels, to slow down, minimise and eventually cease the bleeding. Coagulation or clotting is the process in which blood losses its fluidity and becomes a jelly like mass few minutes after it is shed out or collected in a container.
