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Cephalohematoma is a typically harmless condition that causes blood to pool under a newborn's scalp after a difficult vaginal delivery. Cephalohematoma is a collection of blood between the skull and the periosteum, commonly seen in newborns. Cephalohematoma: Causes, Symptoms And Treatment Cephalohematoma is a condition that occurs in newborns where blood collects between the skull and the periosteum, which is a membrane that covers the bones. This condition is typically caused by pressure or trauma during childbirth, such as the use of forceps or prolonged labor. The collection of blood forms a noticeable swelling on the baby's head, often appearing a few hours after birth. While cephalohematoma can be concerning for parents, it ... Cephalohematoma is a birth injury that causes a blood pool under the scalp, but not in the brain. It usually heals on its own, but may need monitoring or drainage in some cases.