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The atypical Protein Kinase Cs (aPKCs)—PRKCI, PRKCZ and PKMζ—form a subfamily within the Protein Kinase C (PKC) family. These kinases are expressed in the nervous system, including during its development and in adulthood. One of the aPKCs, PKMζ, ... Abstract Establishing and maintaining cell polarity are dynamic processes that necessitate complicated but highly regulated protein interactions. Phosphorylation is a powerful mechanism for cells to control the function and subcellular localization of a target protein, and multiple kinases have played critical roles in cell polarity. Among them, atypical protein kinase C (aPKC) is likely the most studied kinase in cell polarity and has the largest number of downstream substrates ... The PAR3-aPKC-PAR6 complex (the aPKC-PAR complex) is among the most well-studied “polarity proteins” that play fundamental roles in cell polarity in a variety of biological contexts. It is one of the core signaling cassettes containing a protein kinase... You can create a release to package software, along with release notes and links to binary files, for other people to use. Learn more about releases in our docs. Contribute to APk4c -APK/ apk4c -apk development by creating an account on GitHub.
