sincere (comparative more sincere or sincerer, superlative most sincere or sincerest) Genuine; meaning what one says or does; heartfelt. quotations Learn the meaning of sincere , an adjective that describes someone or something that is not hypocritical or deceitful, but honest and genuine. Find synonyms, related words, and usage examples of sincere in British and American English. The meaning of SINCERE is free of dissimulation : honest. How to use sincere in a sentence. Synonym Discussion of Sincere . Sincere definition: free of deceit, hypocrisy, or falseness; earnest.. See examples of SINCERE used in a sentence.