4 meanings: 1. characterized by or requiring a sitting position 2. tending to sit about without taking much exercise 3. (of.... Click for more definitions. Sedentary definition : characterized by or requiring a sitting posture.. See examples of SEDENTARY used in a sentence. SEDENTARY meaning : 1. involving little exercise or physical activity: 2. used to refer to organisms that do not ever…. Learn more. Sedentary means spending a lot of time sitting down and not moving, or staying and living in the same place or area. Learn how to use this word in different contexts with pictures, pronunciation and synonyms.