Regret definition : to feel sorrow or remorse for (an act, fault, disappointment, etc.).. See examples of REGRET used in a sentence. As we delve into the meaning of regret , we embark on a journey through the human psyche, exploring the intricate dance between our actions, our emotions, and the paths we ultimately choose. Regret Meaning and Origin Regret is a feeling of sadness, disappointment, or remorse over something that has happened or something one has done or failed to do. REGRET definition : 1. a feeling of sadness about something sad or wrong or about a mistake that you have made, and a…. Learn more. Learn the meaning , pronunciation and grammar of the word regret , a noun that expresses a sad feeling about something that has happened or something that you have done or not done. See examples, synonyms and related phrases for regret .