Prazosin is used in the treatment of Hypertension (high blood pressure), Heart Failure, Raynaud's disease. View Prazosin ’s uses, side-effects, drug interactions, expert advice and user FAQs only on 1mg.com. Prazosin is an Antihypertensive agent belonging to Alpha Adrenergic blockers. Prazosin is used in the treatment of Hypertension. It is also used to treat posttraumatic stress disorder-related nightmares and sleep disruption, the Raynaud phenomenon. The absolute bioavailability of Prazosin is 43-67% Prazosin hydrochloride: More than half a million bottles of prazosin hydrochloride, a common blood pressure medication, have been recalled by Teva Pharmaceuticals after tests found traces of a ... Prazosin is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly.