Oedema is a build-up of fluid in the ankles, feet or legs that can be caused by various factors. Learn how to recognise, treat and prevent oedema and when to see a GP. Wearing compression garments and reducing salt in the diet often relieves edema. When a disease causes edema, the disease needs treatment, as well. Edema is swelling in parts of your body because of fluid trapped in your tissues, most often in your feet, ankles and legs. Edema, also spelled oedema , is the build-up of fluid in the body's tissue, often affecting the legs or arms. It can have various causes, such as heart failure, kidney problems, infections, or medications, and may have different symptoms depending on the affected organ or area.