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We would like to show you a description here but the site won’t allow us. MCV measures the average size of red blood cells and can help diagnose different types of anemia. A high MCV may indicate vitamin B12 or folate deficiency, liver disease, or other conditions. Discover the MCV meaning in a blood test. Learn what Mean Corpuscular Volume measures, its normal range, and its significance in diagnosing health conditions. MCV, or Mean Corpuscular Volume, is a critical parameter in your complete blood count (CBC) test. It measures the average size of your red blood cells and provides valuable insights into your overall health. An abnormal MCV level—either too high or too low—can indicate underlying health conditions that may require attention.