The word “ indispensable ” comes from the Latin indispensabilis, meaning “that cannot be dispensed with” or “not able to be set aside.” It entered the English language around the late 16th century, maintaining its core meaning of something crucial or essential. Master the word " INDISPENSABLE " in English: definitions, translations, synonyms, pronunciations, examples, and grammar insights - all in one complete resource. Indispensable is a strong adjective for something that you couldn't do without. If you have asthma and you're packing for summer vacation, your inhaler is indispensable , unless you enjoy gasping on the beach. Indispensable definition : Absolutely necessary; essential.Formerly a friend and disciple of Mazzini, with whom he had broken on the question of the monarchical form of government which Crispi believed indispensable to the unification of Italy, he had afterwards been one of Garibaldis most efficient coadjutors and an active member of the party of action.