Natural immunoglobulin M (IgM) antibodies are pentameric or hexameric macro-immunoglobulins and have been highly conserved during evolution. IgMs are initially expressed during B cell ontogeny and are the first antibodies secreted following exposure to foreign antigens. SEA IGM is an e-commerce portal of the Indian Customs that allows users to track their shipments online. Users need to select a location, enter a master bill number and an image letter to access the enquiry service. Immunoglobulin M (IgM) is the largest and first antibody produced by vertebrates in response to antigens. Learn about its history, structure, function, and molecular requirements for polymerization. IgM antibodies (immunoglobulins) are the first antibodies your immune system makes in response to an infection. High IgM might mean you’ve had a recent infection.
