Godspeed definition: good fortune; success (used as a wish to a person starting on a journey, a new venture, etc.).. See examples of GODSPEED used in a sentence. Explore the meaning of Godspeed , learn about its origins, and understand why it still blesses conversations in daily life. Godspeed synonyms, Godspeed pronunciation, Godspeed translation, English dictionary definition of Godspeed . interj. Used to wish someone success or good fortune, as on a journey.