Gigantism is a rare but significant medical condition characterized by excessive growth and height due to an overproduction of growth hormone. This condition typically arises during childhood or adolescence, before the growth plates in the bones close. Gigantism is a rare endocrine disorder characterized by excessive growth and height significantly above average for a person's age and sex. This condition primarily affects children and adolescents, as it occurs when the growth plates in bones are still open. Gigantism is treatable, and treatments aim to manage pituitary tumor growth, control GH levels, and limit their effects on the body. This article describes what gigantism is, including its... Gigantism occurs when growth hormone hypersecretion occurs before the fusion of the long bone epiphysis and is characterized by tall stature. Acromegaly occurs when GH hypersecretion occurs after the fusion of the epiphysis leading to large extremities and characteristic facies.