Dramamine (dimenhydrinate) is an antihistamine that prevents and treats nausea, vomiting and dizziness caused by motion sickness. Learn how to use it, what side effects to watch out for, and what interactions to avoid. Use Dramamine® motion sickness medicine for prevention and treatment of nausea, vomiting and dizziness associated with motion sickness. Dimenhydrinate is an antihistaminic medication used to treat allergic conditions, vertigo, morning sickness and motion sickness. Learn about its common side effects, drug interactions and available medicines on 1mg.com. Dimenhydrinate is a prescription medication used to prevent Motion Sickness.