Desire is a feeling of wanting something or wishing that something will happen. It can also mean sexual appetite or a request. See synonyms, usage, and related words for desire . Master the word " DESIRE " in English: definitions, translations, synonyms, pronunciations, examples, and grammar insights - all in one complete resource. Desire is usually used not just when you long for any old thing, but for something that is associated with giving great pleasure. Thus, you might want to get an A on a test, but you desire a piece of chocolate cake. DESIRE definition: 1. to want something, especially strongly: 2. to have a strong sexual attraction to someone 3. a…. Learn more.