The circle of Willis (CoW) is an anatomical structure that provides an anastomotic connection between the anterior and posterior circulations , providing collateral flow to affected brain regions in the event of arterial incompetency. The circle of Willis is a junction of several important arteries at the bottom part of the brain. Learn more about its anatomy, function, and more. Learn about the circle of Willis , an anastomotic ring of arteries that connects the internal carotid and vertebrobasilar systems to the brain. Find out its structure, function, sources and clinical relevance with diagrams, quizzes and videos. An overview of the arterial blood supply to the brain, including the anterior and posterior cerebral circulation, in addition to the Circle of Willis .