Centrifugation ; An Overview of Definition, Principle, and Types The majority of research labs will be equipped with several centrifuge types, each with the ability to operate with different rotors. Small tabletop centrifuges can be used to gather DNA strands during ethanol precipitation or to pellet cells. Using an ultracentrifuge, one can separate distinct replicating DNA structures in a sucrose gradient or band plasmid DNA in a caesium chloride gradient. Centrifugation is a mechanical process which involves the use of the centrifugal force to separate particles from a solution according to their size, shape, density, medium viscosity and rotor speed. [1] Learn how centrifugation separates mixtures based on density and size using centrifugal force. Explore the different types, components, and applications of centrifugation in various fields. Centrifugation is the technique of separating components where the centrifugal force/ acceleration causes the denser molecules to move toward the periphery while the less dense particles move to the center.
