Cast of grey's anatomy: Learn about the actors and characters

Learn about the actors and characters who have appeared in the American medical drama series Grey ' s Anatomy since 2005. The show features a racially diverse cast and has won several awards and nominations. Several cast members have come and gone since ' Grey 's Anatomy ' first premiered in March 2005. Twenty-two seasons later, here's a look back at the most shocking ' Grey 's Anatomy ' departures ... The story deepens as the new doctors step into leadership. Emotional fallout from the past season lingers, and big decisions shape the future of Grey Sloan. Legacy characters and fresh faces continue to balance life, loss, and medicine.