Blood clotting , or coagulation , is a complex physiological process that prevents excessive bleeding (hemostasis) when a blood vessel is injured. It involves platelets, clotting factors, and the coagulation cascade to form a stable fibrin clot. Learn about the process of blood coagulation or clotting , the factors involved, the pathways and the disorders. Find out how platelets, fibrin and clotting factors work together to prevent bleeding and form a clot. Discover what causes blood to clot, the role of platelets, clotting factors, and why this process is vital for health. Learn causes, disorders, and treatments. Learn how the body prevents excessive bleeding when a blood vessel is injured. Find out the roles of platelets, clotting factors, and fibrin in the blood clotting process and its disorders.