Learn how chronic inflammation can lead to serious health problems and what foods to avoid or eat to reduce it. Find out how omega-3s, vitamin C, polyphenols, gut-healthy foods and the Mediterranean diet can help fight inflammation. Learn how to reduce inflammation naturally with an anti-inflammatory diet based on whole, nutrient-dense foods that contain antioxidants. Find out which foods to eat and avoid, see a sample menu, and discover the benefits of this diet for your health. Anti-inflammatory diet To reduce levels of inflammation, aim for an overall healthy diet. If you're looking for an eating plan that closely follows the tenets of anti-inflammatory eating, consider the Mediterranean diet, which is high in fruits, vegetables, nuts, whole grains, fish, and healthy oils. Chronic inflammation can lead to weight gain and disease. This article lists 13 foods that have powerful anti-inflammatory effects.